You will want to perform pattern generation with your PXI-6533. Pattern generation uses a clocking signal and on each edge (rising or falling...software configurable) of the clock signal data is latched to/from (depending on whether you're peforming input or output) the 6533. With pattern generation, there is no handshaking being performed and you can have an internal or external clocking signal.
There are both LabVIEW shipping examples and text-based programming examples installed with NI-DAQ that illustrate how to perform continuous pattern generation with a 653x device. You can either search through the LabVIEW examples for 653x devices if you're using LabVIEW or look in the ...\Program Files\National Instruments\NI-DAQ\Examples directory for text-based e
xamples.
I've also included a link to an online tutorial below that describes all of the digital I/O operations.
Digital I/O Applications
http://zone.ni.com/devzone/conceptd.nsf/webmain/467ed254f3a30b1286256a6f00720951#6
I hope this helps.
Regards,
Todd D.
NI Applications Engineer