Enrico,
The X position is the generic "any module can plug in here" position. The keyed positions 1 - 12 are used to prevent someone from removing an I/O module and replacing it with one that is totally different. For example the keying on the FP-AI-100 and FP-AI-110 is identical since the modules have identical pin-outs. By using the key positions, you can prevent someone from (easily) swapping out a FP-AI-110 and placing a FP-DO-400 in it's place which could then drive current into your devices, possibly damaging them.
Regards,
Aaron
LabVIEW Champion, CLA, CPI