I agree with Randy that Hyperterminal is a good starting point to test cabling and communication.
In your program, be careful to serial port initialization (how to set baud rate, parity, data bits and stop bits depends on the language used) and to termination character ([CR] means Carriage return: if you are usng CVI it DOESN'T add CR to the message unless you esplicitly put it in).
Another interesting point is the time the instrument takes to respond to the message: it can vary from message to message and is usually described in the instrument's documentation. If you test for a shorter time, you catch a false 'no response'. You could make a while loop and test in it the number of bytes received, then decide whether to end the loop for timeout or answer recei
ved...
To continue help you, we need some details of your developing environment (CVI or LabVIEW?) and of problems you are having at present.
Hope to hear you soon
Roberto