Two questions:
One, if it's a serial card, then presumably it gives you more serial ports, like COM3, COM4, etc. If so, VISA would see the COM ports, and not the card directly. The drivers for the card should make it so that you see the extra serial ports from the OS. If you don't see the extra COM ports from VISA, then it sounds like the drivers for the card are not installed properly. Do the extra COM ports show up in Device Manager?
Two, you said that you're using a Call Library function to get the data and you want to put it into system memory. Errr.... you just read the data and you have it in memory by definition. Are you saying you need a way to parse the data so it shows up on a graph or something?