Hi gold,
By default, you can still access the Main VI while the subVI is running. Only if you set the subVI to be modal, you can't access the Main VI's front panel, while the subVI is running.
In my attached example, it is possible to access the Main VI while the subVI is running. Notice in the block diagram for the Main VI that the subVI and the rest of the code is running in parallel - that's why the Main VI acts when you click the button.
You could instead of a simple 'Value change' use 'Mouse down' instead if you want.
Have fun!
- Philip Courtois, Thinkbot Solutions