Yes, you usually configure the settings for the SCXI-1141 before you ever make an acquisition. You can set the gain and filter for each channel separately in Measurement and Automation Explorer after you add the SCXI chassis and modules to your Device List. If you are new to SCXI, visit the SCXI installation guide online at http://www.ni.com/support/scxi/.
There are also a couple of jumpers on the module that you can change. The factory default settings are usually fine, but for certain configurations you might want to modify these. Check the SCXI-1141 User Manual for more details on these jumpers.