Hmm... I wonder why you do not want to use event structure (as it's available for both those versions), but, anyway, there is a couple of other possible solutions:
1) Overlaing interested area with a transparent picture control -> this allows you to use its "mouse" property (but, this approach imposes a number of limitations);
2) using a call to appropriate system utilities via dll (i.e. using "call library function" node)