john-
you said you already have the 2D data in a text file, i guess some comma delimeted spreadsheet compatible file? labview has a "Read From Spreadsheet File" vi, and it should import your data right into a 2D labview array. then to sum up the columns, first you probably want to transpose that array, then wire it to a single FOR loop, enabling indexing.
the value that gets passed inside will be a 1D array that is a slice of the 2D array. wire that to a "Sum 1D Array" vi from the math menu, then wire the output to the other edge of the FOR loop, and make sure indexing is enabled. then wire that output to a "Write To Spreadsheet File" using the 1D array input. it should process very fast, and you just have to wire up some stuff like the file path and deli
meters and stuff. did that explain it well enough?
micah