Hi happybird,
I installed the TKTDS instrument drivers and had a look at the TKTDS Read Waveform.vi. I couldn't find any way to change the scale of the waveform graph. The data displayed should be the same that is measured by the scope. Try running the TKTDS 420 Getting Started VI that is located in:
All functions >> Instrument I/O >> Instrument Drivers >> Tktds4xx VIs >> Application Example VI's
I don't have access to a TKTDS 420 myself, but I hope the example VI displays the correct value. If it does then it is a matter of finding out what is different in your VI. Good luck.