Thanks for the help in my post, In this moment I am working sending data by packet of 20 mesure per pack and this is working.
Also I saw that the graph in chart was delaying the program so I decided to graph every second.
I also tried with SerialUSB.flush and doesn't work, do no anithing.
And with wireshark I was monitoring the usb comunication, but I am not sure if the time column is in second. If is in that, the packet is sending every 4.1~4.4 ms, If is like I think, the Arduino is not sending periodically, I should send every 4.0ms (200us*20 mesures). I think that it happend by the way I am timing the period in arduino.
In this moment I am doing the saving data loop and HMI to check if the improvement worked