What do you mean by Labview does not take the first bit which is the direction bit? If the number is a U8, U16, or U32, it is an unsigned integer which means the first bit is part of the number. It it is I8, I16, I32, then the first bit is a sign (+ or -). A2 is a hex number, which is 162 in decimal. How does this relate to 51?
With I2C, your device has to be programmed to respond to a certain address. If you want to use different devices with different addresses, you should contact the device manufacturer to learn how to program the device address. The 8451 will send out the address that you program into the code. There must be a device with that address to respond.