Thanks! You helped me a lot. The problem was really related to VISA resource names. On non-development PCs there were no aliases defined inf visaconf.ini [Aliases] section, that's why I experienced difficulties to get my application working. VISA resource name on front panel of my appl. was named "COM1", and it had to be changed to ASRL1::INSTR in order to fix the problem. Indeed, VISA RTE does not create aliases itself.