I did a little looking through the V+ user manual to try and get an idea of what these ports are. It looks like they are just mechanisms for communicating with external devices. There are certainly many communication methods supported in LabVIEW such as serial, TCP, ActiveX, etc. Depending on what you are communicating with you could use the built in LabVIEW functionality. If it is something that LabVIEW doesn't support natively, you would probably need to look at calling the driver through a potential dll interface using the call library function. Also, it may be possible to convert the V+ code over to a dll or have it act as an ActiveX server - I didn't find any resources on this but you might know how to do it since you have worked in V+.