Depending on the number of bytes and the endian nature of what you're getting, direct use of the Typecast primitive (Advanced>Data Manipulation palette) will work by itself or with a little help moving bytes using Split Number and Join Number primitives (same palette):
There have been a few recent posts on the topic with several example VIs.
http://forums.ni.com/ni/board/message?board.id=170&message.id=105851&query.id=0
http://forums.ni.com/ni/board/message?board.id=170&message.id=104302&query.id=0#M104302
http://forums.ni.com/ni/board/message?board.id=170&message.id=105158#M105158
The "whatever String to Number" functions translate strings of ascii code into the corresponding number, (e.g. a 4 byte string "FFFF" (0x 4646 4646) into a U32 with a value of 65535, etc.)
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Fading out. " ... J. Arthur Rank on gong."