I too experienced a similar problem twice on my machine and I have no idea how to stop it because it is so intermittent and I cannot replicate it.
Perhaps I can offer some clues.
The Labview screen cannot be stopped and some parts of Windows appears frozen. Oddly enough I can switch to the block diagram but thats about all I can do. The LV stop button will indicate a mouse click on it but the VI does not stop. iT also cannot be closed.
Even the reset button and power button on the PC does not work. I am forced to power down the PC (pull the plug) to get back control.
I believe it is related to a visa call to my serial Balance.
ANyway no solution but hopefully some clues.
Dell Optiplex GX260 w/ 500MB RAM
Win2K 500.2195 w service pak 4,
NI
serial Hardware and NI serial ver1.45 (16 com ports)
Labview 6.1 and 7