I ran into a problem last week and I kept getting the error -2146827284. I couldn't find any help online, but I finally found the problem so I thought I would post my solution to possibly help others. The problem was that an excel file had been loaded into the ActiveX Web Browser in a VI and the VI was then saved with the file still loaded. This caused an error when trying to open an excel file using the excel VIs from the Report Generation toolkit. I thought this was interesting since I didn't think the two actions would be related. Anyway...to fix the problem I just removed the old Web Browser with the excel file loaded, replaced it with a new one, and resaved the VI. Hopefully this will save some people some pain in the future.
~jc