Hello Kaustubh,
I think that's a very bad idea...
A user will be very frustrated/confused if he moves the mouse but doesn't see the pointer on the screen (or only for a short moment).
Better catch the mouse clicks with an event structure and deicde what to do with them...
Best regards,
GerdW

using LV2016/2019/2021 on Win10/11+cRIO, TestStand2016/2019