I am not sure, but I suspect you want LabVIEW to open a new instance of Excel if Excel is already running in the background. To my knowlege, it is not possible to open a new instance of Excel although it is very easy to open new books in the already opened Excel. Many of our example Excel code will do just that. If you want to exit out of Excel, use an invoke node entitled "Quit". If you want Excel to be invisible, use the property node entitled "Visible" and set it false. Wire both of the nodes to the application reference created for Excel.
Jeremy Braden
National Instruments