Thanks, Tbob..
I've tried both com1, ASRL1::INSTR and com2 as you noted, none of those help, including with reboots. Meanwhile, not even needing reboots, the older serial routines still work (not at the same time of course..) to com1 or com2.
I also tried the VISA Close, then a 50ms timer, then a VISA Open, another 50ms timer, then the VISA Write, then a timer, and loop back to the start. Nada.
I am wondering now if NI VISA is requiring hardware handshaking of some kind - that's what it's looking like, and the serial port has only three wires on it, so there's no handshaking available. When I try to click on VISA Write, nothing opens up to show me the internal guts of the VI - is this a setting of some kind, or isn't NI allowing examination of their i
nternals anymore?
Thank you!