Greetings,
The alarm message "No Communication response from modbus secondary" means that communication cannot be established between the modbus object and your external device. Verify that you have set up the serial port settings properly and that you have configured the modbus object. Verify that your external device is functioning properly and connected to the PC. If all of these things are ok, you may need to increase the receive gap of the serial port settings and the receive timeout of the modbus object. There is a tutorial on the web which outlines the troubleshooting steps for communication in Lookout.
http://zone.ni.com/devzone/conceptd.nsf/webmain/033CD84BAC7E1E7586256A3300756284?opendocument
I hope this information is helpful. Have a good day!
Patrick R.