I'm not sure exactly what you're looking for here, but I'll try and give you some pointers. You should be able to use the VisaNS .NET API to communicate over serial, GPIB, TCP, and numerous other bus types. Any data you read back from a device could be parsed into a numeric value and used to set the values of our controls. If you are Measurement Studio Professional or higher, you can use the Instrument IO Assistant to help you determine the commands you need to send to your instrument and to parse the results. You can get information on how to use the Instrument IO Assistant from the "Creating a Measurement Studio 488.2 or VISA Application" topic in our online help.