Hi mastada,
The IMAQVision.ParticleMeasurement method has an 'area' item that will, after a calibration, return a value in terms of the associated unit. In fact, I believe all of the ParticleMeasurement types return a calibrated result. You might give this function a try, I think it could be just what you need. As always, these functions are detailed in the VB function reference for Vision.
In fact, with Vision an example is shipped that utilizes this function. You can find it at:
..\Program Files\National Instruments\Vision\Examples\MSVB\2. Functions\Calibration\NonLinearCalibration.vbp
Good luck,
Robert Manion
Applications Engineering
National Instruments