Hi Kevin,
Of course this will take a little work, but CWSerial should be able to handle this without too much hassle. Take a look at the example program usually included in C:\Program Files\National Instruments\MeasurementStudio\VB\Samples\Instr\Basic Serial
You should be able to use this example as a starting point.
Hope this helps out!!!
Best Regards,
Aaron Kobayashi
Application Engineer
National Instruments