Pells,
what you are looking for is differential input configuration where you connected the both inputwires. This inputconfiguration is called "differential" because it only measures the difference between two inputwires. Since the offset of your inputs is about 5V, i am sure that you need no further signalconditioning (which nevertheless could improve your readings).
Since the difference you want to measure is about +- 50 mV, you should create a task with this voltage range. The driver of the device, NI-DAQmx, sets the gain to an appropriate value for you, so you don't need to calculate that four yourself....
hope this helps,
Norbert B.
Norbert
----------------------------------------------------------------------------------------------------
CEO: What exactly is stopping us from doing this?
Expert: Geometry
Marketing Manager: Just ignore it.