mekanika,
I'm a little confused by your question so I'll talk about 2 scenarios.
1. You want to build an .exe without the LV Run-time Engine or NI-DAQ.
This is fine as long as your target machine has (at least) the LV Run-time engine installed as well as NI-DAQ if DAQ is used in the program. Simply leave the create installer box unchecked when you build the .exe.
2. You want to run a LV .exe without having the LV Run-time engine or NI-DAQ installed.
This is not possible. The .exe needs (at least) the LV run-time engine to execute properly. NI-DAQ is only needed if the application calls the NI-DAQ VIs.
Hope this helps.