Hello JPO,
The DIO on the 6120 can be clocked at 10Mbps. However, you will have to implement the serial protocol yourself in software. You can set line 0 to be output and use it to clock. Then depending on what you serial protocol is and whether you are reading or writing, you will decide on the directions of the other lines.
If you provide more information about your serial protocol, I may be able to help you further.