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NI-PXI Serial not responding

Hi.

My problem is that MY PXI-8431 is not sending data out.

I have a PXI Chassis connected via a MXI-4 to the PC (PC#1). I have a loopback connector on the card (Port1 is looped back to itself). I use a standard terminal (RealTerm) to send a string and see that it is received.

I then remove the MXI-4 from PC#1 and place it in PC#2 (running the same operation system). The setup (loopback connector) is left untouched. I can see that all the hardware is identified in the MAX application. BUT!!! when use the same terminal application, I cannot see the loopback. 

How is that possible?

There are screenshots attached (The Original PC works fine, the new PC DOES NOT work)

Thanks

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