If you are using the SCXI-1127 in independent mode the wire mode setting in MAX is irrelevant. This setting is only used when the SCXI-1127 is not used in independent mode.
In Independent mode you are free to activate any relay that you like. You are responsible for setting Hlselect and 1Wire according to the wire mode desired (1-wire or 2-wire)
Refer to this support document:
http://sine.ni.com/apps/we/niepd_web_display.DISPLAY_EPD4?p_guid=B45EACE3E95956A4E034080020E74861&p_node=DZ52331&p_submitted=N&p_rank=&p_answer=&p_source=External
If you are not using independent mode, you cannot set the wire mode on a per channel basis programmatically. You need to close the Switch session and open a new one with a different topology;16x1, 32x1, or 64x
1 which will set the switch in 4, 2 and 1-wire respectively.