Mr Ed,
As AnujD's reply showed, you should NOT use NI's 68-to-50 pin adapter. You'll need to find another way to map the PCI counter's signals to your test equipment. If you truly cannot change the existing cable, you'll need to make a little interface board that maps from you 50-pin cable to the CORRECT pins of your new 68-pin device.
Your old PC-TIO-10 has 10 counters. How many are being used? What functions do they perform? The PCI-6601 that you mentioned has only 4 counters while the 6602 sister product has 8 counters. Though the raw channel count is lower, these new counter/timer boards are in every other way a HUGE improvement. Hopefully you'll get to take advantage of some of the new features (buffered measurements, digital triggering, quadrature encoder interface, digital filtering, duty cycle changes on-the-fly, etc.)
You should also be aware that just as there isn't a true drop-in replacement on the hardware side, neither will the new counters act as a drop-in replacement on the software side. The driver calls that are used for the PC-TIO-10 counters are not the right ones to use to program a 660x device.
Good luck with the upgrade!
-Kevin P.
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