Hi, Kloke,
Another thing that you should try changing is the way File I/O is done in your loop. As Salvador stated, the Write to Spreadsheet File VI opens, writes and closes the file every single time it is called. This definitively adds some overhead to your application, which at the end can be translated into more time for each iteration to execute. I will recommend you follow a different architecture, in which you first Open the file outside the loop, Write inside the loop, and Close the file once you press the stop button. I am attaching a picture of a simplified version of the block diagram. You should see a difference in performance after implementing an architecture like this.
I hope this helps!
GValdes