Hi,
I not exactly sure what you are trying to do here. We have RS 485/422 cards that work just like a RS-232 port. The DIO could be used for communication, but it would be slow was the protocol would be implemented in software. If you are looking to analyze a 422 line, the DIO could definatly do that.
As for GPIB, you can check out the driver at www.ni.com/downloads, and there in manuals o' plenty at ww.ni.com/manuals.
Let me know more about what you are trying to do with the 422 problem, and I'll do my best to help you out!
Best Regards,
Aaron K.
Application Engineer
National Instruments