I have 4.0.1 and 6.0.3RT on one PC - all seems ok, but never ran both at the same time. Also, another PC has 5.1.1 and 6.0.3RT and also no problem. I have each version stored in its own folder, and try to not interchange them at all.
Have you considered just using the 6.0.2 version and use the "Save To Version 5.0" as needed? This might allow you to simplify your PC programs.
Doug