Hello Karl,
Thank you for using our discussion forum. Yes, the IMAQ Vision does support 10 bit images. Monochrome images with bit depths greater than 8-bits are stored in a 16-bit image format. You can use the IMAQ Histogram.vi included with the IMAQ Vision Development Module to construct the histogram of a 10-bit image.
Regards,
Nipun M
Applications Engineer
National Instruments