Serial poll and SRQ have to do with the GPIB control of the instrument. SRQ stands for Service ReQuest. When sending GPIB commands over the IEEE488 bus, certain bits are set/reset in a register that give information about the bus transactions. One bit can be set if an error occurs. Another bit can be set when an operation is complete, signaling the sender that it is OK to send another command. By polling the bus, you can clear out the status register that holds these bits. If an error occured previously, and you send another command without polling the status register, your new command would probably not get executed. Polling ensures that the line is cleared so that the next command can be sent without some pending action needing to be performed. It gets a lot more complicated. Look up the IEEE488 spec (search the web) if you need more info. Also, many instrument manuals give an overview of status registers, serial polling, and SRQs.