You can certainly use System Exec.vi to launch NI Spy. To do that, wire the path to your NISpy.exe file into the command line input of System Exec.vi. For instance, on my machine (LV 7.1 installed), I wire "C:\Program Files\National Instruments\NI Spy\NISpy.exe" into the command line input and, when I run the VI, NI Spy opens. However, closing it programmatically is a different story. I can't find any way to do this. To make this possible, we would need one of two ways. First, if there were an ActiveX server for NI Spy, we could control it that way, but I searched for you and could not find anything like that registered on my machine. The second option is to close it via System Exec.vi which would require us to be able to do this through the command window "Start>>Run>>cmd". I've search and searched on Google but can't find a command that does this. Therefore, it may be that you can open it programmatically and the user can close it. I hope this helps you out.