Well, I think I may or may not have found a clue... we have two devices, the PXI rack being one of them, that we configured to use the same IP address, since only one of them will ever be on the network at the same time. So in theory we could swap between them with minimal effort. I noticed that even though the switch we were plugged into had been powered off and reset, still has a destination that has the other device's MAC address. I don't know if this is the issue or not, but it has me highly suspicious.