Except for things like scales on graphs and charts, indicators can't be changed while a VI is running. To completely disable a control or indicator you have two options. From the front panel, right click on the control and select Advanced>Enabled State. From the diagram, create a property node for the control, right click on it and choose Change to Write. Right click on the property node again and select the Disabled property. Wiring a value of 0 to the property node enables the control, a 1 disables it, and a 2 disables it and grays it out.