The NI RS-232 comms library doesn't allow you to change the baud rate, number of data bits, stop bits, parity etc. unless you close the port and re-open it. If you need to do that, you will have to use the Windows API for communications instead.
This is a bit of a nuisance. I recently had to implement a protocol where the first byte of a message was indicated by being sent with a different parity, and the delay required to close and reopen the port between bytes using the NI libraries was unacceptable.
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Martin.
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Martin
Certified CVI Developer