Daco,
you should compare USB to an internal PC bus like PCI rather than to an
RS232 port. For devices plugged into the PC for most people it's clear
that they need a driver from the vendor of these devices to be able to
communicate with them. In many cases a driver is available as a DLL but
sometimes device vendors provide also ActiveX controls as an API for
the driver.
Due to the protocol overhead ActiveX doesn't provide the best performance but depending on the implementation the interface might be pretty easy to use. If there is a well documented DLL available you could also use this DLL in LabVIEW (Call Library Node) as a DLL call is typically much faster than an ActiveX call.
In LabVIEW there is also an option to talk directly to the USB by using NI-VISA calls but then you would have to implement the complete protocol that's used by the Phidget device and as there is already a driver available I wouldn't recommend this option.
Best regards,
Jochen Klier
National Instruments Germany