You will need to set the gain of each channel using the AI_Read function. The input range parameter of AI-Configure is acutually ignored for E Series devices. The polarity parameter will allow you to set the range to unipolar (0 to 10 V) or bipolar (-5 to +5).
You use the gain parameter of the AI_Read to futher specify the input range. The valid gain settings for the 16E-4 can be found on page A-2 of the appendix in the user manual linked below. For a +/- 100 mV range you would set the polarity of AI_Configure to bipolar and the gain parameter to 50 of the AI_Read. I hope this helps.
PCI E Series User Manual
http://digital.ni.com/manuals.nsf/webAdvsearch/06F1C9FB0D0BA5C286256C010057461B?OpenDocument&vid=niwc&node=132100_US
Regards,
Todd D.