Hello Shay,
If you are using Windows 2000/NT and your drive in which TestStand is located is partinoned as NTFS, you can set security permissions on folder or on a file basis. You should check your security settings for the folder \Cfg. This folder contains all the INI files that store the station options, and search directory settings. You may have the folder set to deny write access, when it should be set to full control. You can access the security options by right-clicking on the file/folder and selecting Properties from the context menu. Hope this helps.