Hello Sachin,
Do you know if your instrument supports this action through software? We discussed your issue here and I'd suggest you to make sure first if 'dc bias isolation' can be set on and off through software on hp 4284. If yes, then a vi can be written for this. However, as you have already mentioned, we'll still need to find out what string command is required for this communication (from manuals,datasheets,etc.)
Again, thank you for choosing National Instruments!
Swapnil P.
National Instruments Engineer