These are details that are important to include. So, when you use a single port on the same pc, it doesn't work with either Hyperterminal or LabVIEW but if you use two separate pc's it works. If that is the case, then I would think that the whole problem is with the little serial loopback you have on the single pc. Make sure it is a real short by using an ohmeter and verify that it is really pins 2 and 3 and not pins 3 and 4. If you using something like a paper clip, make sure the connections are tight. I prefer to use a male plug and solder wires on the back.