Chromatography analysis .vi

[CIETodd@UB]

Does anyone have a chromatography .vi that they could share?  The thought of writing one seems a little daunting and someone must have dealt with this before. 

I ran into this a while ago and wrote a .vi for integration under a TOC curve.  It works ok but requires operator attention.  I'm looking for a .vi that can automatically identify the peaks, integrate them and then save the instrument output data (volts vs time) and integration results.

Alternatively, a .vi to process the output data file (volts vs. time) would be fine.  I could collect the chromatographic data and analyze it in a seperate .vi .

Thanks for any help you could offer.

[Mathan]

search the forum with chromatography. you can find a couple of help.

[ezra46]

Did you ever get anywhere with this ?

I looked around a lot for software, found peakfit, which seems sophisticated, but doens't work, a bunch of primitive stuff I couldn't get to work, some stuff that is free, but requires the data to be in a chromatography file format.

The thing that works the best, although not that well, is IgorPro; the interface is a little wierd, but it seems to do ok, although the baseline handling is not good, and the program clearly has hiccups.

Origin pro also does this, although i didnot like their interface

regards,

ezra s abrams

Sage Science

32 Tozer Rd

Beverly, MA

ezra@sagescience.com

[Tanya_V]

Hi Ezra,

How are you going to be acquiring your data and what kind of analysis will you want to perform? We don't have any VIs precifically designed for chromatography analysis, but we do have curve fitting and peak detection VIs. Here are two Developer Zone Tutorials that describe Curve Fitting Models and Methods in LabVIEW and Peak Detection in LabVIEW. I hope this helps!

Take care!

[Batiston]

Hi 

Did you get a chromatography .vi for labview? I am looking for one. Could you help me?

Thank you, very much.

[WillyWad]

Hello Batiston,

We do not have any VIs specifically designed for chromatography, as mentioned above. That said, I officially suggest using the Curve Fitting Models and Peak Detection functionality linked in the post directly above yours, if these include what you need.

Unofficially, it looks like a third-party has created a chromatography toolkit for use with LabVIEW. I found some information on that here. This is not something officially tested or supported by NI. I just read through the document I linked and thought it may include some of what you're looking for. I hope this is helpful, but please proceed at your own accord here.

Otherwise, maybe the OP will respond with what they ended up using, even though it was quite some time ago. 

Let me know if you have other questions.

Regards,

William 

Applications Engineering

[Batiston]

Hello WillyWad

Thank you very much for guidance. I have read about chromatography toolkit. It seems exactly that I am looking for. I sent e-mail to them and at moment I haven't a return yet. Besides, you must pay for chromatography toolkit. About this, I thought very expensive (my opinion). Probably the project dimensionality is highly complexity.

I will research about Curve Fitting Models and Peak Detection functionality. Any help would be interesting and well coming!

Again: thank you very much

[WillyWad]

I saw another post on our forums where someone mentioned trying to put together a High-Performance Liquid Chromatography (HPLC) system. There wasn't any additional information in that forum post, but it gave me some pointers on what to look for (as I'm not personally familiar with chromatography). 

This helped me find a publication about implementing a LabVIEW-controlled HPLC system. It looks like you may have to pay for the publication (I'm not sure how much it is). I though I'd at least let you know it's there and you would be able to assess if it's helpful for you. Here's a link.

Hope that helps!

Regards,

William

Applications Engineer

[Batiston]

Thank you very much Willian. Excuse me for my delay in the answer!

I saw the abstract this paper. Unfortunately I don't have the access it. But, it seems have superficial concepts. However, it seems excellent to turn Labview more famous in the new education trends! 

In our group of research, a researcher developmented VI LabView to separation analysis like HPLC, CE... However,  this VI Labview there are some limitations, like: i) it isn't possible have zoom in chromatography peaks and ii) it isn't possible have the integration of peak area. 

If I send to you our project VI, could you help us to put zoom in our VI Labview project?

If we had zoom in chromatography peak, it will help us a lot. However, before I send you, I need the approbation of my friend researcher PhD.

Thank you very much Willian!

Best regards

[FinchTrain]

Hi,

What specific graphs are you trying to use? You may not be able to zoom given that LabVIEW does not allow zoom (though some graphs allow you to view specific windows of data).

Based on your description, my thought of an alternative approach would be to write the waveform data to file with timestamps, and then replot the specific timeframe of interest. This way you could look at a smaller window of data in greater depth.

With more information about the specific graphs you are using and any other relevant information (are you writing waveform data to file?) we can assist you going forward. Unfortunately we cannot take an entire project and modify it for you.

Regards,

Finch Train