You can always find out whether or not something will run in the run-time engine by looking at its LabVIEW help entry. Alternately, you can try it, but the help file is a lot easier. In general, if it changes code, you will not be able to use it in the run-time engine, since the run-time engine does not include a compiler. If it involves inspection, you can probably do it. Note that inspection of the block diagram on executables is a somewhat dicey proposition. It won't work if the block diagram has been stripped. This sort of thing is usually done as part of development.
Please note that "scripting" is an overloaded term. I like to restrict its use to code creation and modification, using "VI server" or "methods" or "properties" for other things, such as inspection. Unfortunately, this is not the norm on these forums, where "scripting" is used to denote any VI server use.
