Brian_T,
    Thanks for that link about compiling a shared library for use on a VxWorks cRIO.  The only thing they mention that I don't understand is this bit:
"GNU toolchain distributed with Wind River VxWorks"
I have been unable to locate a compiler for VxWorks so I am assuming that is located in this GNU toolchain thing?  Does that come with the cRIO?  I think I noticed a VxWorks C compiler somewhere else online but we're talking a totally different product I would have to purchase, assuming it would even work.  I guess once the stub and the shared library are all good to go, I just call the C functions in the shared library and when it comes time to talk to the serial port, just slap a VISA Read/Write VI on the block diagram.  I've been using a cRIO and COM1 access for some time now so I do understand at least that much.  Let me know how to get ahold of this "toolchain" thing.  Thanks.