Definitely you will want configure an alias to your USBTMC instrument and copy your visaconf.ini to your target machine.
Unlike other traditional GPIB instruments, it is unlikely that your USB device has the same address when connected to another computer. Therefore, use VISA aliases that allow you to configure your USB device outside of your application.
To learn more about VISA and USB, you the following app note is helpful:
Using NI-VISA 3.0 to Control Your USB Device