I guess my first question would be are all these channels going to be on one card? Are you going to just make single measurements (are you interested in instantaneous values vs. "waveforms")? Doing a "Sample channels" for instance will make a single measurement of several channels (on the same board) and present you with an array of the resulting data, one element per channel. How fast do you need to sample, are all of the signals going to be on the same board? The latest NI-Daq allows configuring tasks that mix channel types (T'couples, straight voltage measurements, etc.) which makes configuring the DAQ easier.
If you can give us a little more information regarding what you are trying to accomplish it will help.
P.M.
PutnamCertified LabVIEW Developer
Senior Test Engineer North Shore Technology, Inc.
Currently using LV 2012-LabVIEW 2018, RT8.5

LabVIEW Champion