I'm having identically the same problem under XP, 2000, and 98, with DAQCards AI-16XE-50 and 6024E on a Dell desktop (Optiflex GX260)with a Ricoh 5C476 PCMCIA to PCI adapter. I'm using the native MS pcmcia driver and NI-DAQ 6.9.3. Under XP, the DAQCard gets assigned IRQ 19, the same as the Cardbus controller, and same as with Eoin's machine, I can't change the IRQ's. Thoughts?